Methylphenidate affects task-switching and neural signaling in non-human primates

ConclusionsMethylphenidate impaired task-switching performance, which can be used as a measure of cognitive flexibility. This detriment may result from degraded outcome signaling within the PFC. This study has implications for the use of MPH in the treatment of ADHD.

Source: Psychopharmacology - February 17, 2020 Category: Psychiatry Source Type: research