Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals
Conditions: HIV Infections; LTBI Interventions: Drug: Dolutegravir (DTG); Drug: Isoniazid (INH); Drug: Rifapentine (RPT); Drug: Antiretroviral Therapy (ART); Dietary Supplement: Pyridoxine (Vitamin B6) Sponsors: National Institute of Allergy and Infectious Diseases (NIAID); ViiV Healthcare (VH) Not yet recruiting
There has been greater recognition of allergy and autoimmune disease in pediatric solid organ transplantation, however, their relationship with pediatric heart transplant is unclear. The purpose of this study was to explore post heart transplant immune dysregulation.
AbstractThe panorama of food allergies (FA) has changed profoundly in recent years. In light of recent advances in knowledge of pathogenetic mechanisms and a greater attention to the multifaceted range of possible clinical manifestations, there is a need for a critical review of past classifications. Changes in nutrition, environment and lifestyles around the world are modifying the global FA epidemiology and new FA phenotypes are also emerging. Furthermore, both biotechnological advances in this field and recent personalized therapies have improved the diagnostic and therapeutic approach to FA. Consequently, both the prev...
AbstractNeuropathic pain (NeP) is an intractable pain caused by a lesion or disease of the somatosensory nervous system. NeP is often challenging to manage because most of the mechanisms remain to be elucidated. Recent investigations in the field of autoimmune neurology have demonstrated that specific autoantibodies against antigens in the somatosensory pathway can cause NeP. Detection of pathogenic autoantibodies in NeP adds to the understanding of the mechanism of pain, which might aid in the development of novel immunotherapies. Therefore, it is necessary to explore novel NeP ‐related autoantibodies to improve the man...
ConclusionSmaller tissue transfers are less prone to infections of the recipient site and present low LOS. For an POABP regime, the combination of 2nd and 3rd generation cephalosporins presents substantial results in recipient site infections. In cases of allergy, potential pathogens show adequate susceptibility to moxifloxacin.Clinical relevanceA combination of 2nd and 3rd generation cephalosporins may be used to prevent recipient sites in head and neck surgery.
Widespread use of nonmedical masks could reduce community transmission. But recommending their broad use could also cause a run on the kind of masks that health care workers desperately need.
Professional societies issue stern warning not to inappropriately prescribe meds for COVID - 19
Publication date: Available online 31 March 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Suvina Amin, Mena Soliman, Andrew McIvor, Andrew Cave, Claudia Cabrera
Publication date: Available online 31 March 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Bruce T. Miles, Sofianne Gabrielli, Ann Clarke, Harley Eisman, Greg Shand, Moshe Ben-Shoshan
Condition: Malaria, Malaria Vaccine, Insecticide-treated Bednets Interventions: Biological: RTS,S/AS01 malaria vaccine; Other: PBO bed nets Sponsors: Michigan State University; University of Malawi College of Medicine; University of Maryland, College Park; Boston University; National Institute of Allergy and Infectious Diseases (NIAID) Recruiting
Condition: Cow Milk Allergy Intervention: Dietary Supplement: Amino acid-based formula Sponsor: Assiut University Not yet recruiting