Mesenchymal stem cell-derived exosomes rescue oxygen-glucose deprivation-induced injury in endothelial cells.

CONCLUSION: Both MSCs and MSC-derived exosomes attenuated OGD-induced rat primary brain endothelial cell injury. These findings suggest that at least some of the protective effects of MSCs on endothelial cells are mediated by MSC-derived exosomes.
PMID: 32056526 [PubMed - as supplied by publisher]

Source: Current Neurovascular Research - February 12, 2020 Category: Neurology Authors: Kong LY, Liang MY, Liu JP, Lai P, Ye JS, Zhang ZX, Du ZM, Yu JJ, Gu L, Xie FC, Tang ZX, Liu ZY Tags: Curr Neurovasc Res Source Type: research