Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent.

Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent.
Magn Reson Med Sci. 2020 Feb 13;:
Authors: Fujita N, Nishie A, Asayama Y, Ishigami K, Nakayama T, Ushijima Y, Kakihara D, Takayama Y, Morita K, Ishimatsu K, Takao S, Yoshizumi T, Furusyo N, Honda H
Abstract
We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.
PMID: 32051362 [PubMed - as supplied by publisher]

Source: Magnetic Resonance in Medical Sciences : MRMS - February 12, 2020 Category: Radiology Authors: Fujita N, Nishie A, Asayama Y, Ishigami K, Nakayama T, Ushijima Y, Kakihara D, Takayama Y, Morita K, Ishimatsu K, Takao S, Yoshizumi T, Furusyo N, Honda H Tags: Magn Reson Med Sci Source Type: research