Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein

The spike glycoprotein of the newly emerged SARS-CoV-2 contains a potential cleavage site for furin proteases. This observation has implications for the zoonotic origin of the virus and its epidemic spread in China. The membrane of coronaviruses harbors a trimeric transmembrane spike (S) glycoprotein (pictured) which is essential for entry of virus particles into the […]
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information bat coronavirus COVID-19 epidemic furin SARS-CoV-2019 spike glycoprotein viral viruses Wuhan zoonosis Source Type: blogs