Development of Obsessive-Compulsive Symptoms Following Abrupt Discontinuation of Venlafaxine

Withdrawal symptoms after discontinuation of antidepressants are common and have long been known. Typical symptoms after dose reduction or discontinuation of antidepressants are dizziness, drowsiness, headache, flu-like symptoms, hyperarousal, imbalance, insomnia, irritability, and nausea. Rebound, relapse, or recurrence associated with the underlying mental disorder may also occur. The occurrence of obsessive-compulsive symptoms (OCS) following abrupt discontinuation of antidepressants have not yet been reported. Here we report the development of OCS (obsessional suicidal thoughts) in a patient with major depressive disorder and absence of a previous obsessive-compulsive disorder following abrupt discontinuation of venlafaxine. Treatment with escitalopram facilitated remission of OCS. We discuss a possible causal link between abrupt discontinuation of venlafaxine and development of OCS under consideration of pathophysiologic aspects regarding obsessive compulsive disorders, the chronological sequence of symptoms in the present case, and pharmacodynamic and -kinetic aspects. Our case report suggests the possibility of the occurrence of obsessive-compulsive symptoms following abrupt discontinuation of venlafaxine.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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CONCLUSION: there were an expressive quantitative number of absences due to depression, in which it was observed, especially, that the absence time remained long. PMID: 32491123 [PubMed - in process]
Source: Revista Latino-Americana de Enfermagem - Category: Nursing Authors: Tags: Rev Lat Am Enfermagem Source Type: research
CONCLUSION: depressive symptoms are associated with burden of comorbidities, greater number of disease complications, hemodialytic intercurrences and functional dependence. Physical exercise practice can be an effective care strategy. PMID: 32490957 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research
CONCLUSION: Quality of life and social support were identified as protective factors for depressive symptoms while being at risk of malnutrition, living alone, reporting pain and being female are predictors. PMID: 32490955 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research
SafetyLit note (June 2020): This publication uses the ISTIC as its DOI registry. Thus, in some nations, this DOI may not forward to the publisher website for obtaining full text. Objective To understand the epidemic characteristics and trends of suicid...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
CONCLUSION: LT4-induced SCH, which is a part of traditional DTC treatment, can exacerbate the anxiety symptoms in patients and disrupt their quality of life, depending on the level of fT4. PMID: 32490648 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
Authors: Meregildo ED Abstract Neurocysticercosis (NCC) is a global health problem. In more developed countries, NCC is mainly a disease affecting immigrants. In developing countries, NCC is the most common parasitic disease of the nervous system and the main cause of acquired epilepsy. NCC is also an unrecognized cause of strokes and could account for 4%-12% of strokes. Here, I report a case of a 58-year-old woman who presented to the emergency department (ED) with severe headache, vomiting, and sudden loss of consciousness. Multiple NCC and Fisher grade 4 aneurysmal subarachnoid hemorrhage (SAH) were demonstrated...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
Authors: Pagani G, Zanchetta N, Galimberti L, Oreni L, Passerini S, Giacomelli A, Cordier L, Gismondo MR, Rizzardini G, Galli M, Antinori S Abstract Dengue Fever (DF), transmitted by Aedes mosquitoes, is the most common arthropod-borne infection, it is almost ubiquitous in tropical and subtropical areas with an estimate of 360 million infections per year. A competent vector (A. albopictus) is present in most of Southern Europe and is endemic in Italy. We conducted a 16-year retrospective study of probable/confirmed dengue fever observed at the Department of Infectious Diseases of Luigi Sacco Hospital in Milan, Ital...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. However, other non-dopaminergic neuronal systems such as the serotonergic system are also involved. Serotonergic dysfunction is associated with non-motor symptoms and complications, including anxiety, depression, dementia, and sleep disturbances. This pathology reduces patient quality of life. Interaction between the serotonergic and other neurotransmitters systems such as dopamine, noradrenaline, glutamate, and GABA controls the activity of striatal neurons and are particularly interesting for understan...
Source: Frontiers in Neuroanatomy - Category: Neurology Source Type: research
In 2019, the Congressional Black Caucus convened an emergency Taskforce to examine Black Youth Suicide and Mental Health. The Taskforce released its report in December 2019, highlighting several recommendations for increased research, intervention development, and community engagement. In collaboration with the Office of Behavioral Health Equity at SAMHSA, this 90-minute interactive roundtable webinar featured co-authors of the Taskforce report, including the leader of the Taskforce, answering our most pressing questions about Black youth suicide.
Source: National Institute of Mental Health - Category: Psychiatry Authors: Source Type: news
Jun 11, 2020. . Sponsored by Great Lakes PTTC, Prevention Technology Transfer Center Network
Source: Rural events via the Rural Assistance Center - Category: Rural Health Source Type: events
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