Evaluation of anti-Xa activity after injection of a heparin lock for dialysis catheters in intensive care: A prospective observational study

Acute kidney injury (AKI) is a serious and frequent complication in the intensive care unit (ICU) [1] and can require the initiation of renal replacement therapy (RRT). Venous catheters are currently the preferred vascular access route for patients with AKI who require RRT [2,3], but there is a risk of catheter infection or thrombosis. To prevent these complications, lock solutions are instilled into the lumen of the hemodialysis catheter after each session and left in place until the next use. Sodium citrate and heparin locks are widely used.

Source: Thrombosis Research - February 10, 2020 Category: Hematology Authors: Julien Bovet, Agn ès Soudry-Faure, Hamid Merdji, Eléa Ksiazek, Jean-Pierre Quenot, Ferhat Meziani, Amélie Cransac, Julie Helms Tags: Letter to the Editors-in-Chief Source Type: research