Myoviridae phage PDX kills enteroaggregative Escherichia coli without human microbiome dysbiosis.

Conclusion. PDX killed EAEC isolate EN1E-0007 in vivo and in vitro, while not altering the diversity of normal human microbiota in anaerobic culture, and thus could be part of an effective therapy for children in developing countries and those suffering from EAEC-mediated traveller's diarrhoea without causing dysbiosis. PMID: 32011231 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32011231?dopt=Abstract

Source: Journal of Medical Microbiology - February 2, 2020 Category: Microbiology Authors: Cepko LCS, Garling EE, Dinsdale MJ, Scott WP, Bandy L, Nice T, Faber-Hammond J, Mellies JL Tags: J Med Microbiol Source Type: research