Clinicopathological significance of lipocalin 2 nuclear expression in invasive breast cancer

ConclusionsTumour cell expression of LCN2 plays a role in breast cancer progression with loss of its nuclear expression which is associated with aggressive features and poor outcome. Further functional analysis is warranted to confirm the relationship between the subcellular localisation LCN2 and behaviour of breast cancer.

http://link.springer.com/10.1007/s10549-019-05488-2

Source: Breast Cancer Research and Treatment - January 31, 2020 Category: Cancer & Oncology Source Type: research