Association between REM sleep behavior disorder and impulsive –compulsive behaviors in Parkinson’s disease: a systematic review and meta-analysis of observational studies

AbstractBackgroundBoth REM sleep behavior disorder (RBD) and impulsive –compulsive behaviors (ICBs) are well-recognized non-motor features in patients with Parkinson’s disease (PD). Studies have given contradictory results about the potential association between RBD and ICBs.MethodsPubMed, Embase (via Ovid), and the Cochrane Central Registry of Controlled Trials (CENTRAL) databases were systematically searched till August 20, 2019 to identify studies that explored the possible correlation between RBD and ICBs in patients with PD. Two authors independently screened records, extracted data and evaluated quality of included studies. Pooled odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were calculated by employing a random or fixed-effects model. We performed subgroup and sensitivity analyses, and we assessed potential publication bias.ResultsA total of 134 references were screened and 10 studies involving 2781 PD patients were included. Overall, RBD was associated with a more than twofold higher risk of developing ICBs (OR 2.12, 95% CI 1.43 –3.14,I2 = 56.7%,P 
Source: Journal of Neurology - Category: Neurology Source Type: research

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The geriatric population is at high risk of severe low blood glucose (LBG) events due to diminished homeostatic mechanisms, especially on hypoglycemic medications. Moderate to severe LBG events in these patients can contribute to behavior changes such as agitation, change in level of consciousness, disruption of sleep, instability and increased risk of myocardial infarction, stroke and falls. Rapid recognition and appropriate treatment and prevention of LBG and recurrences can reduce risk for hospitalization in the geriatric population.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Source Type: research
CONCLUSIONS.: Our results confirm the multidimensional nature of mania. Hyperactivity, increased speech, and thought disorder appear as core features of the clinical construct. The mood experience could be heterogeneous, depending on the co-occurrence of euphoric (elevated mood) and dysphoric (irritability and depressive mood) emotions of varying intensity. Results are also discussed regarding their relationship with other constitutive elements of bipolar disorder, such as mixed and depressive states. PMID: 32093802 [PubMed - in process]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Publication date: Available online 25 February 2020Source: NeuroImage: ClinicalAuthor(s): Bart van den Munckhof, Anne F. Zwart, Lauren C. Weeke, Nathalie H.P. Claessens, Joost D.J. Plate, Alexander Leemans, Hugo J. Kuijf, Heleen C. van Teeseling, Frans S.S. Leijten, Manon J.N. Benders, Kees P.J. Braun, Linda S. de Vries, Floor E. Jansen
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: Available online 25 February 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Su-Ying Cui, Yuan-Li Huang, Xiang-Yu Cui, Hui-Ling Zhao, Xiao Hu, Yu-Tong Liu, Yu Qin, Nurhumar Kurban, Yong-He Zhang
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Conclusions/Importance: This study revealed that many users are not responsibly using CBD products, many believe CBD products provide health benefits that are not yet scientifically proven, and they are not knowledgeable about legal and regulatory issues. Until CBD use is more thoroughly researched and has more comprehensive regulation, public health professionals should address alternative stress and anxiety treatment methods. PMID: 32093530 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
Conditions:   Sleep Hygiene;   Sleep Intervention:   Behavioral: Sleep Hygiene tips Sponsors:   Medical College of Wisconsin;   Divine Savior Holy Angels High School;   Children's Hospital and Health System Foundation, Wisconsin Recruiting
Source: - Category: Research Source Type: clinical trials
The dopamine fast, created by California psychiatrist Dr. Cameron Sepah, has very little to do with either fasting or dopamine. As Sepah told the New York Times, “Dopamine is just a mechanism that explains how addictions can become reinforced, and makes for a catchy title. The title’s not to be taken literally.” Unfortunately, with such a snazzy name, who could resist? This is where the misconceptions begin. What’s the thinking behind a dopamine fast? What Sepah intended with his dopamine fast was a method, based on cognitive behavioral therapy, by which we can become less dominated by the unhealthy...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Addiction Health trends Mind body medicine Stress Source Type: blogs
Was wondering if any practicing sleep medicine physicians could comment on job satisfaction. I've heard from some that sleep medicine is repetitive and boring.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Sleep Medicine Source Type: forums
On some days – or sometimes during weeks or even months – life is just hard and tough. And you may start to think to yourself that you might as well give up on your new habit, current goal or most important dream. This week’s post is all about that. And about the timeless wisdom from the past few thousands of years that can help you to stay strong, to nudge yourself back on the right track again and to keep going towards what you deep down want and dream about. Never Give Up Quotes That Will Help You to Stay Strong “When you get into a tight place and everything goes against you, till it seems as t...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - Category: Consumer Health News Authors: Tags: Personal Development Source Type: blogs
Conclusion: The combination of JW-SZRD with lorazepam can significantly improve sleep quality with fewer AEs. It is an effective treatment and superior to lorazepam alone for chronic insomnia. PMID: 32089719 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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