Surgical Treatment of Osteonecrosis of the Jaw: An Emerging Problem in the Era of Bisphosphonates

Bisphosphonates are increasingly used to treat many conditions including osteoporosis, bony cancer metastases, and multiple myeloma.1  Although generally safe, bisphosphonates carry a small risk of osteonecrosis of the jaw (ONJ).2 ONJ results in exposed necrotic bone in the jaw and may require surgical treatment. Given the rise of bisphosphonate use over the past decade,3 we aimed to evaluate 1) the change in the incidence of ONJ , 2) trends in the surgical treatment of ONJ, and 3) patient-level predictors of surgical treatment.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: OTHER Source Type: research