An old plant virus inspires the design of a modern vaccine to fight against malaria

(Walter Reed Army Institute of Research) WRAIR scientists demonstrated that a novel, second-generation malaria vaccine candidate based on the tobacco mosaic virus may offer protection against Plasmodium falciparum malaria. Malaria, infecting approximately 228 million individuals in 2018, remains a meaningful threat to public health, regional stability and deploying Service Members. This research shows that the TMV coat protein can also be highly effective as a vaccine scaffold to refocus the host immune system to the most vulnerable epitopes on circumsporozoite protein.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news