Trends in the Proportion of Time Spent Outpatient While Receiving Antibiotics for Treatment of Gram-Negative Rod Bacteremia Among Allogeneic Hematopoietic Cell Transplant Recipients

Gram-negative rod bacteremia (GNRB) is a leading cause of morbidity and mortality among allogeneic hematopoietic cell transplant (HCT) recipients. Historically, GNRB has been treated with inpatient intravenous antibiotic therapies. However, outpatient antibiotic delivery has been shown to lower costs, decrease complications and may reduce rates of hospital-acquired multidrug-resistant organism (MDRO) infections. Despite such advantages, there are no data assessing trends in outpatient management of GNRB among allogeneic HCT recipients nor on the impact changing resistance profiles have on such trends.

Source: Biology of Blood and Marrow Transplantation - January 24, 2020 Category: Hematology Authors: Margaret L. Lind, Steven Roncaioli, Amanda Phipps, Catherine Liu, Andrew Bryant, Ania Sweet, Steven A. Pergam Tags: 492 Source Type: research