Characterization of the active components of the multimerized sTNFRII-adiponectin fusion protein showing both TNF α-antagonizing and glucose uptake-promoting activities.

Conclusion：In summary, the hexamer and trimer of sTNFRII-adiponectin fusion protein had both TNFα-antagonizing and glucose uptake-promoting activities, although neither could improve glucose uptake in the cell model of insulin resistance. PMID: 31965947 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research