Combining antigen detection and serology for the diagnosis of selected infectious diseases

Publication date: Available online 20 January 2020Source: Methods in MicrobiologyAuthor(s): Maria M. Plummer, Charles S. PaviaAbstractImmunoassay detection of specific antigens and host-produced antibodies directed against such antigens constitute two of the most widely used and successful methods for diagnosing infectious diseases and many of the non-infectious autoimmune disorders. We will be reviewing some of the epidemiology, microbiology, and clinical aspects of selected organisms and discuss their diagnosis by describing some of the major antigen detection systems and serologic techniques available to health care providers. The pathogens to be discussed include Streptococcus pyogenes, Streptococcus pneumoniae, Legionella pneumophila, Helicobacter pylori, Coccidioides immitis, and Cryptococcus neoformans.
Source: Methods in Microbiology - Category: Microbiology Source Type: research