Adjusted tight control blood glucose management in diabetic patients undergoing on pump coronary artery bypass graft. A randomized clinical trial

AbstractBackgroundMany of the patients who are undergoing Coronary Artery Bypass Graft have diabetes mellitus or metabolic syndrome and are at risk for hyperglycemia events.ObjectiveThe present study aimed to compare conventional glucose control with adjusted tight control in patients undergoing on-pump CABG.MethodsThis double –blind randomized clinical trial study was conducted in Shiraz, Iran, from September 2017–March 2018. Two consecutive groups of 75 patients undergoing elective on- pump coronary artery bypass graft surgery.InterventionThe patients were divided into adjusted tight control of the blood glucose between 100 and 120  mg/dl and conventional method that the blood glucose maintained ≤200 mg/dl.Primary outcomes weremortality, sternal wound infection, cardiac arrhythmia, cerebrovascular attack, and acute renal failure.Secondary outcomes includedduration of mechanical ventilation and length of ICU staying. The same main outcomes were evaluated after one month.Statistical analysisThe data were analyzed using SPSS version 20(SPSS, Chicago, IL). Group comparisons were performed using t-tests and Chi-square tests. Repeated measurement test was used for comparing blood glucose in two groups. Mann Whitney U test was compared duration of the mechanical ventilation and length of ICU staying. Statistical significance was defined as ap value
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research

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Source: Microchemical Journal - Category: Chemistry Source Type: research
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Source: Revista Brasileira de Epidemiologia - Category: Epidemiology Source Type: research
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Source: Revista Brasileira de Epidemiologia - Category: Epidemiology Source Type: research
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Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
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Authors: Totzeck M, Rassaf T Abstract Cardiotoxic side effects can significantly limit the quality of life and survival of tumor patients under treatment. Acute and chronic effects include hypertension, venous and arterial thromboembolic events, acute and chronic coronary syndromes, heart failure and arrhythmias. Patients with previous cardiovascular diseases are often more frequently affected by side effects. The triggers are not only irradiation and conventional chemotherapy but increasingly also newer forms of cancer treatment. These include targeted therapy and immune checkpoint inhibitors (ICI). The goals of o...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
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Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
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