Obesity, metabolic syndrome and olfactory perception.

[Obesity, metabolic syndrome and olfactory perception]. Rev Neurol. 2020 Jan 16;70(2):53-66 Authors: Rebolledo-Solleiro D, Solleiro-Villavicencio H, Velasco M, Roldán-Roldán G Abstract Nowadays, it is well accepted that obesity and metabolic syndrome are diseases that constitute a global public health issue. In consequence, the interest in the study of the effects these pathologies produce in the central nervous system has greatly increased in the last decades. One of the most overlooked topics in the literature is the impact they exert in sensory systems, among which is olfaction. The olfactory system is related to a number of vital functions, like the activation of defense mechanisms, contribution to appetitive and digestive reflexes, recognition of conspecifics, and even has socio-sexual implications. It has been discovered that the olfactory system also plays a crucial role in food intake, the choice of foods, appetite and satiety mechanisms; therefore, it is involved in obesity development. Clinical studies have proven that obese patients exhibit hyposmia more frequently than aged-matched healthy controls. Olfactory alterations have also been found in obese rodents or in animals with similar features of human metabolic syndrome. The causes of this association are still being investigated. This work reviews the studies that have tried to understand this association from a preclinical and clinical approach as well as those biological mec...
Source: Revista de Neurologia - Category: Neurology Authors: Tags: Rev Neurol Source Type: research

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Source: Journal of Spinal Disorders and Techniques - Category: Surgery Tags: Primary Research Source Type: research
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Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
AbstractPurpose of ReviewThe epidemiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) is continuously evolving with an increasing life span and the prevalence of metabolic diseases, including obesity, diabetes, cardiovascular disease, and hypertension. As a result, there is a substantial financial strain on health care.Recent FindingsRecent studies and clinical trials have strengthened the relationship of known risk factors of BPH and LUTS. These include metabolic syndrome, diabetes, obesity, hypertension, and elevated serum dihydrotestosterone. Excessive consumption of red meat, saturated...
Source: Current Bladder Dysfunction Reports - Category: Urology & Nephrology Source Type: research
(Natural News) The World Health Organization (WHO) defines overweight or obesity as the abnormal or excessive accumulation of fat that presents a health risk. Obesity is caused by either one of two things: genetics or an increased consumption of high-calorie foods coupled with a sedentary lifestyle. People with obesity suffer from abnormalities characteristic of metabolic syndrome...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
This study investigated whether the levels of specific serum microRNAs (miRNAs) were altered following diet-induced weight loss and whether the serum miRNAs differed in the presence of the metabolic syndrome. METHODS: The study was a weight loss intervention trial with a prescribed energy deficit of approximately 500 kcal/d. Levels of 22 miRNAs were determined in serum samples from 85 participants with overweight or obesity. miRNAs were analyzed using TaqMan Array miRNA Cards and normalized to the geometric mean of spiked-in ath-miR-159a and U6 small nuclear RNA using the ΔCT method. RESULTS: The avera...
Source: Obesity - Category: Eating Disorders & Weight Management Authors: Tags: Obesity (Silver Spring) Source Type: research
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