Heat shock transcription factor 1 regulates exercise-induced myocardial angiogenesis after pressure overload via HIF-1 α/VEGF pathway.

In conclusion, exercise training encourages cardiac ontogeny by means of HSF1 activation and successive HIF-1α/VEGF up-regulation in endothelial cells during continued pressure overload. PMID: 31930683 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31930683?dopt=Abstract

Source: J Cell Mol Med - January 11, 2020 Category: Molecular Biology Authors: Tian X, Zhou N, Yuan J, Lu L, Zhang Q, Wei M, Zou Y, Yuan L Tags: J Cell Mol Med Source Type: research