Serological Evidence of Yersiniosis, Tick-Borne Encephalitis, West Nile, Hepatitis E, Crimean-Congo Hemorrhagic Fever, Lyme Borreliosis, and Brucellosis in Febrile Patients Presenting at Diverse Hospitals in Kenya

Vector-Borne and Zoonotic Diseases, Ahead of Print.
Source: Vector-Borne and Zoonotic Diseases - Category: Infectious Diseases Authors: Source Type: research

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This study aimed to investigate the expression and function of FSTL5 in HCC and its role in EMT. METHODS: FSTL5, E-cadherin and vimentin in HCC, and paracancerous tissues were detected by immunohistochemistry. Correlation of FSTL5 expression with overall survival was assessed. The proliferation and invasion of HCC cell lines SK-Hep1 and MHCC-LM3 were analyzed by cell counting kit-8 and Transwell assays. The expression of FSTL5, E-cadherin, and vimentin in HCC cells was examined by polymerase chain reaction and Western blot analysis. T-test was used to analyze the difference in proliferation and invasion ability betwee...
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Objectives: Our goal was to evaluate the effect of antiviral therapy on hepatocellular carcinoma incidence for cirrhotic patients with lower hepatitis B virus DNA levels. Methods: Consecutive cirrhosis patients from a US cohort (n = 381) and 408 patients from a Taiwan cohort were enrolled. Patients were classified into a low (
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research
Conclusion Our program should be considered as a proof of concept, which confirmed the feasibility of a HCV-microelimination program at the scale of an HIV clinical unit. However, 12 months were not sufficient to achieve our objective despite the specific organization.
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research
Coronoviraus disease 2019 (COVID-19) has infected over two million people worldwide and the number keeps growing every day. While the pulmonary complications of COVID-19 are obvious, the effect of the virus on the other organs and the chronicity of the organ dysfunction remain unknown. The virus causes a debilitating infection with multiorgan injury and has a high mortality rate estimated to be around 3.70%. Several hypotheses are formulated to explain the liver dysfunction in COVID-19 patients which include collateral damage from cytokine storm, drug-induced liver injury, viral-induced hepatitis and hypoxia-induced damage...
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Case Reports Source Type: research
We present the unique opportunity we had to monitor the liver, IL-6 and immune cell course before, during and after COVID-19 in a boy with autoimmune hepatitis (AIH) and type 1 diabetes (T1D). CD4+ and CD8+ T cells frequencies decreased because of prednisolone, followed by a plateauing increase whereas CD19+CD20+ B cell increased strongly and was unaffected by COVID-19 infection. Moreover, the percentage of activated CD8+ T cells expressing HLA-DR (CD8+HLA-DR+) increased during COVID-19 and subsided after its clearance. Total regulatory T cells (Tregs: CD4+CD25+CD127lowFOXP3+) remained stable. Although activated Tregs (CD4...
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Case Reports Source Type: research
Scott LincicomeSeeking to prove theold adage about roads and good intentions, Missouri Senator Josh Hawley has recently introduced legislation,The Slave ‐​Free Business Certification Act of 2020, that would impose steep fines and other penalties on large companies doing business in the United States, unless they regularly audited their global supply chains and certified that theyand their suppliers did not utilize “forced labor.” The bill’s presumed intent is to discourage slave labor around the world – a goal that ’s both laudable and, given troubling reports out of China and elsewhe...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
MIDDLEBORO (CBS) — Massachusetts has its first human case of eastern equine encephalitis of 2020, the state’s Department of Public Health reported Monday. The EEE patient is a male under the age of 18 and was exposed in Middleboro. In Plymouth County, the EEE risk level is “critical” for Middleboro and Carver, and high for Plympton, Kingston and Rochester. Both Carver and Middleboro have banned outdoor activities on town properties from dusk until dawn. EEE has been found in 29 mosquito samples this year, the state says. The EEE risk map for Massachusetts. Green indicates a remote risk, Blue is low,...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Syndicated Local EEE Middleboro News Source Type: news
Publication date: Available online 2 August 2020Source: Antiviral ResearchAuthor(s): Darci R. Smith, Connie S. Schmaljohn, Catherine Badger, Kristen Ostrowski, Xiankun Zeng, Sheila D. Grimes, Jonathan O. Rayner
Source: Antiviral Therapy - Category: Virology Source Type: research
Publication date: Available online 2 August 2020Source: Ticks and Tick-borne DiseasesAuthor(s): Cheyne Kurokawa, Sukanya Narasimhan, Aurobind Vidyarthi, Carmen J. Booth, Sameet Mehta, Lea Meister, Husrev Diktas, Norma Strank, Geoffrey E. Lynn, Kathy DePonte, Joseph Craft, Erol Fikrig
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Conditions:   Chronic Hepatitis b;   Hepatitis B Reactivation Intervention:   Drug: Vemlidy Sponsors:   National Taiwan University Hospital;   National Taiwan University Hospital, Yun-Lin Branch;   Taipei City Hospital;   Chiayi Christian Hospital;   Dalin Tzu Chi General Hospital;   E-DA Hospital;   Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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