257. Nonmedical Use of Prescription Opioids, Heroin Use, Injection Drug Use, and Overdose Mortality Among Adolescents

Nonmedical use of prescription opioids (NUPO) among adolescents is decreasing. However, given the evolving epidemiology of the drug overdose epidemic as well as the association between NUPO and heroin use, NUPO in adolescents is still an important issue. Understanding interrelationships between NUPO and illicit opioid use in adolescents can inform prevention efforts. The purpose of this study is to present the magnitude of the drug overdose problem in adolescents and understand heroin use and injection drug use (IDU) in the context of NUPO.
Source: Journal of Adolescent Health - Category: Child Development Authors: Source Type: research

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Authors: Hanna MN, Chambers C, Punyala A, Iqbal A, Singh B, Oruc C, Prakash P, Prajapati Y, Wang Y, Amery Ai Z, Shechter R, Speed TJ, Koch CG, Williams K Abstract The use of opioid analgesics for pain management has increased dramatically over the past decade, with corresponding increases in negative sequelae including overdose and death. Physicians, policymakers, and researchers are focused on finding ways to decrease opioid use and overdose. This crisis calls for a coordinated response that includes the entire healthcare sector. In this work, the authors lay out a blueprint for such a response at the level of the...
Source: Journal of Opioid Management - Category: Addiction Tags: J Opioid Manag Source Type: research
CONCLUSIONS: Utilization of drugs that harness endogenous opioid antinociception in accordance with varying physiological states represents a novel approach for effective pain management while mitigating the present epidemic of death by synthetic opioid overdose. PMID: 32091619 [PubMed - as supplied by publisher]
Source: Journal of Opioid Management - Category: Addiction Tags: J Opioid Manag Source Type: research
(University of Pennsylvania School of Nursing) As opioid overdoses continue to grab headlines, more states are providing their communities with easier access to naloxone, which can prevent death by reversing opioid overdoses. But while naloxone may be available at township buildings, libraries, or other community locations, little is known about how schools maintain a supply and use naloxone to prepare for treating overdose.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
CONCLUSIONS: Given increasing rates of opioid addiction and death, viable solutions are universally needed. Successful intervention measures should be widely shared between military, veteran, and civilian healthcare and public health communities. Increased collaboration between these groups could inculcate successful programs to prevent and decrease opioid use. Results received from recent military and veterans' programs for prescription and electronic medical record (EMR) monitoring and data sharing may also prove useful for civilian healthcare providers and hospital systems. Future evaluations from ongoing federally fund...
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
The rates of opioid overdose in the United States quadrupled between 1999 and 2017, reaching a staggering 130 deaths per day. This health epidemic demands innovative solutions that require uncovering the key brain areas and cell types mediating the cause of overdose — opioid-induced respiratory depression. Here, we identify two primary changes to murine breathing after administering opioids. These changes implicate the brainstem's breathing circuitry which we confirm by locally eliminating the µ-Opioid receptor. We find the critical brain site is the preBöt zinger Complex, where the breathing rhythm origin...
Source: eLife - Category: Biomedical Science Tags: Human Biology and Medicine Neuroscience Source Type: research
OBJECTIVE: Drug overdoses among men have historically outnumbered those among women by a large margin. Yet, U.S. research on the first wave of the opioid epidemic involving prescription opioids has found women to be at increased risk. The current study con...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
CONCLUSIONS: Overdose deaths seem to have returned to a historically familiar pattern of dominance by younger males. Our findings suggest the gender-age distribution in deaths to specific opioid types must be considered for effective intervention. PMID: 32048603 [PubMed - in process]
Source: Journal of Studies on Alcohol and Drugs - Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research
New largescale study in the American Journal of Preventive Medicine found overprescription of opioids by dentists common, particularly to patients at high risk for substance abuse, and that almost 1/3 of patients received more powerful drugs than neededElsevierIMAGE: In this cross-sectional analysis of 542,958 dental visits by adult patients, between 1 in 4 and 1 in 2 opioid prescriptions exceeded the recommended morphine equivalents and days'supply for...viewmore Credit: Michelle S. Woods Ann Arbor, February 4, 2020 - Dentists are among top prescribers of opioids in the US, however, whether their opioid prescrib...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
BOSTON (AP) — Massachusetts health officials said Wednesday the rate of opioid-related overdose deaths in the state fell an estimated 5% from its 2016 peak. The decline comes despite the growing presence of the synthetic opioid fentanyl as a driver of opioid-related overdose deaths, according to the Massachusetts Department of Public Health. In 2019, the opioid-related overdose death rate was 29 per 100,000 people. In 2016, it was 30.5 per 100,000 people. According to the report, there were 2,023 confirmed and estimated opioid-related overdose deaths in 2019. For the same period in 2016, there were 2,097 confirmed op...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health opioid crisis opioids Source Type: news
MONDAY, Feb. 10, 2020 -- In the midst of a U.S. epidemic of opioid abuse, knowing how to quickly administer the anti-overdose drug naloxone could save a life. Now, research finds that delivering naloxone via nasal spray could be the quickest and...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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