RCPCH demands urgent action on air quality

Air pollution single greatest environmental threat to public health in the UK, especially for children and deprived communities Related items fromOnMedica Pollution kills 1.7 million children, says WHO Should we have compulsory measles vaccination at school entry? Multidrug-resistant TB spreads less easily than ‘normal’ TB Fewer lung symptoms in children as air pollution levels drop Texting can improve flu jab uptake
Source: OnMedica Latest News - Category: UK Health Source Type: news

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The Gaithersburg biotech's latest move reflects its fundamental strategy: Watch for opportunities to address a virus outbreak.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Companies aim to have vaccine in production within 16 weeks before entering testing stageThere are no vaccines or treatments approved for the new coronavirus, but the race is on to develop one.This week the Coalition for Epidemic Preparedness Innovations (Cepi)announced it would commit $11m ( £8.4m) to three programmes led by the companies Inovio Pharmaceuticals, Moderna and the University of Queensland.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Science China World news Asia Pacific Medical research Vaccines and immunisation Health Source Type: news
lde;o LGP Abstract Varicella in adults and immunocompromised patients can be severe. The clinical diagnosis of varicella has high accuracy and the history of disease has a high positive predictive value for protection. A significant portion of adults, however, cannot remember if they have had varicella, especially older individuals. We conducted a cross-sectional study to determine the seroprevalence of varicella protective antibodies titers in adults with no clinical history of disease, attended at a Reference Center for Special Immunobiologicals and Travel Medicine in Rio de Janeiro (Brazil). Titration of immuno...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research
What is a coronavirus? Coronaviruses are a group of viruses that cause diseases in mammals, including humans, and birds. Why are they called coronaviruses? The name derives from the fact that the viral capsule has a “halo” or “crown” surrounding it. What do coronaviruses do? In humans, the virus infects the airways giving rise to flu-like symptoms, a runny nose, cough, sore throat and fever, these are usually mild, but in rare cases can be lethal. Is there a vaccine against coronaviruses? No. Are there any drugs to block or treat infection? No. When were coronaviruses first discovered? In the 1960s ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - Category: Science Authors: Tags: Sciencebase Source Type: blogs
In a clinical trial of patients vaccinated after chemotherapy-induced remission with patient-derived AML cells fused with autologous dendritic cells (DC/AML fusions) we demonstrated durable AML-specific immunity. 71% of patients sustained long-term remission from AML at 55-91 months (responders) while those who experienced relapse had recurrence at 2-26 months (non-responders).
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 14 Source Type: research
Children undergoing hematopoietic stem cell transplant (HSCT) lose their prior immunity post-allogeneic transplant and need reimmunization post-transplant. Traditionally, immunizations post-HSCT were administered at a pediatrician's office (PO), but studies in adult patients have shown compliance with re-vaccination to be low and no data exists on adherence in pediatrics. An internal audit of HSCT patients who received vaccinations at a PO revealed delays in starting vaccines when eligible, non-completion of the schedule in its entirety happened often, and there was an extended length of time for completion of the schedule.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 106 Source Type: research
CAR T cells have demonstrated unique potency for tumor cytoreduction and durable response in hematological malignancies. However, disease relapse remains a concern due to the emergence of antigen negative variants, tolerization of CAR T cell populations and lack of T cell persistence. We postulated that vaccination with a personalized cancer vaccine, that we developed, in which patient derived tumor cells are fused with autologous dendritic cells would enhance CAR T cell efficacy through the expansion of T cell clonal populations and the vaccine mediated enhancement of T cell activation and persistence.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 54 Source Type: research
Gram-negative rod bacteremia (GNRB) is a leading cause of morbidity and mortality among allogeneic hematopoietic cell transplant (HCT) recipients. Historically, GNRB has been treated with inpatient intravenous antibiotic therapies. However, outpatient antibiotic delivery has been shown to lower costs, decrease complications and may reduce rates of hospital-acquired multidrug-resistant organism (MDRO) infections. Despite such advantages, there are no data assessing trends in outpatient management of GNRB among allogeneic HCT recipients nor on the impact changing resistance profiles have on such trends.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 492 Source Type: research
Given the significant morbidity from infection after HCT, guidelines have recommended re-vaccination starting at 6 to 12 months post-tx. Guideline adherence, however, has been varied across institutions.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 564 Source Type: research
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Local TV Source Type: news
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