Is Ca2+ Essential for Synaptic Vesicle Endocytosis?

Is Ca2+ Essential for Synaptic Vesicle Endocytosis? Trends Neurosci. 2020 Jan 03;: Authors: Chanaday NL, Kavalali ET Abstract Synaptic vesicle fusion is coupled to swift retrieval of vesicle components from the synaptic plasma membrane. Ca2+ has been assumed to be a key mediator of this coupling. In a recent study, Orlando et al. unequivocally demonstrate that Ca2+ is not essential for synaptic vesicle retrieval. PMID: 31910996 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31910996?dopt=Abstract

Source: Trends in Neurosciences - January 2, 2020 Category: Neuroscience Authors: Chanaday NL, Kavalali ET Tags: Trends Neurosci Source Type: research

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