Blood-Brain Barrier KCa3.1 Channels: Evidence for a Role in Brain Na Uptake and Edema in Ischemic Stroke [Basic Sciences]

Conclusions— BBB endothelial cells exhibit KCa3.1 protein and activity and pharmacological blockade of KCa3.1 seems to provide an effective therapeutic approach for reducing cerebral edema formation in the first 3 hours of ischemic stroke.

http://stroke.ahajournals.org/cgi/content/short/46/1/237?rss=1

Source: Stroke - December 22, 2014 Category: Neurology Authors: Chen, Y.-J., Wallace, B. K., Yuen, N., Jenkins, D. P., Wulff, H., O'Donnell, M. E. Tags: Acute Cerebral Infarction Basic Sciences Source Type: research