CREB/CRTC-mediated regulation of transcription is important for regulatory T cells
Conclusion: Our data point to an activation of CREB/CRTC-mediated transcription in naturally occurring as well as in in vitro induced Tregs. CREB knockdown reduced the formation of iTregs suggesting a possible role of this pathway in immune tolerance.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Bartel, S., Kastle, M., Eickelberg, O., Krauss-Etschmann, S. Tags: 5.3 Allergy and Immunology Source Type: research
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