Functional cell phenotype induction with TGF- β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair.

In conclusion, TGF-β1-containing collagen-PU constructs can induce the functional cell phenotype of human AF cells in vitro and in situ. This combined cellular, biomaterial and bioactive agent therapy has a great potential for AF tissue regeneration and rupture repair. PMID: 31899537 [PubMed - in process]
Source: European Cells and Materials - Category: Cytology Tags: Eur Cell Mater Source Type: research