Targeting Plasmodium Plasmepsin V: Hitting Two Birds with One Stone.

Targeting Plasmodium Plasmepsin V: Hitting Two Birds with One Stone. Trends Parasitol. 2020 Feb;36(2):85-87 Authors: Brancucci NMB, Heussler VT, Grüring C Abstract A recent report by Jennison et al. reveals an important role for plasmepsin V (PMV), an aspartyl protease, in the development of malaria transmission stages. The authors showed that PMV activity is critical for protein export in these stages and that specific PMV inhibitors block parasite transmission to mosquitoes. PMID: 31883707 [PubMed - in process]
Source: Trends in Parasitology - Category: Parasitology Authors: Tags: Trends Parasitol Source Type: research