Glioma: Targeting a histone mutant
Nature Reviews Cancer 15, 2 (2015).
doi:10.1038/nrc3885
Author: Sarah Seton-Rogers
Oncogenic mutation of histone H3.3 occurs frequently in paediatric brainstem gliomas. Funato et al. created a model of the aggressive brainstem glioma diffuse intrinsic pontine glioma (DIPG) using human embryonic stem cells (ESCs). Early neural progenitor cells (NPCs) were derived from ESCs and then
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Sarah Seton-Rogers Tags: Research Highlight Source Type: research
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