Oral and sublingual immunotherapy for food allergy: current progress and future directions.

Oral and sublingual immunotherapy for food allergy: current progress and future directions. Curr Opin Immunol. 2013 Aug 20; Authors: Moran TP, Vickery BP, Burks AW Abstract Food allergies are increasing in prevalence and present an emerging epidemic for westernized countries. Strict dietary avoidance is the only approved management for food allergy, but accidental exposures regularly occur, leading to significant patient anxiety and decreased quality of life. Over the past decade, oral and sublingual immunotherapies have emerged as potential treatments for food allergy. While several small clinical trials have demonstrated that immunotherapy can desensitize food-allergic individuals, strategies for further enhancing safety and definitively establishing long-term efficacy are needed. This review presents an overview of recent oral and sublingual immunotherapy trials, and provides a glimpse into what the next generation of food immunotherapy may entail. PMID: 23972904 [PubMed - as supplied by publisher]
Source: Current Opinion in Immunology - Category: Allergy & Immunology Authors: Tags: Curr Opin Immunol Source Type: research

Related Links:

Authors: Chen Y, Sun J, Liu H, Yin G, Xie Q Abstract Chimeric antigen receptor T (CAR-T) cells are T cells engineered to express specific synthetic antigen receptors that can recognize antigens expressed by tumor cells, which after the binding of these antigens to the receptors are eliminated, and have been adopted to treat several kinds of malignancies. Autoimmune diseases (AIDs), a class of chronic disease conditions, can be broadly separated into autoantibody-mediated and T cell-mediated diseases. Treatments for AIDs are focused on restoring immune tolerance. However, current treatments have little effect on imm...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
ConclusionsSeizure detection devices provide moderate or greater anxiety reduction among the majority of people with epilepsy and their caregivers, but current translatability into improvements in overall HR-QOL may be limited. Affordability and technological support are potential barriers to maximizing benefit equally among the epilepsy community. These considerations may be useful to help guide future device development and inform patient–clinician discussions on device usage and HR-QOL.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Authors: Abbing AC, Baars EW, Van Haastrecht O, Ponstein AS Abstract Anxiety is a major problem for many individuals, causing impairment in daily life. Art therapy is often deployed and although positive results are communicated in clinical practice, its effectiveness and working mechanisms have hardly been studied. Therefore, it is important to systematically describe the intervention process and to detect the working mechanisms to be able to evaluate them. Narrative case studies help to understand the intervention in more depth. A typical case file was selected for case reporting according to scientific (CARE &am...
Source: Case Reports in Psychiatry - Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research
Authors: Xi Y, Yu H, Yao Y, Peng K, Wang Y, Chen R Abstract This is the first study to investigate the mechanism of Post traumatic stress disorder (PTSD) after the 2017 7.0 Ritcher scale Jiuzhaigou earthquake. In order to identify the mechanism underling interactions among different factors associated with PTSD symptoms. Three months after the earthquake, 607 participants from the heavy damaged areas were recruited in this survey. Demographic information and scale measurements on social support, resilience, anxiety, depression, and PTSD were collected using standardized questionnaire. The result showed that PTSD, a...
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
Publication date: Available online 22 February 2020Source: Microbes and InfectionAuthor(s): Jason A. TetroAbstractOne of the most perplexing questions regarding the current COVID-19 coronavirus epidemic is the discrepancy between the severity of cases observed in the Hubei province of China and those occurring elsewhere in the world. One possible answer is antibody dependent enhancement (ADE) of SARS-CoV-2 due to prior exposure to other coronaviruses. ADE modulates the immune response and can elicit sustained inflammation, lymphopenia, and/or cytokine storm, one or all of which have been documented in severe cases and deat...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
Conclusions: Caregivers of children with CD may experience difficulties that impact their well-being; specific difficulties identified included the impact of caregivers’ social activities, finances, and anxiety. The findings detailed in this review point toward factors that may guide health care personnel to provide support for the caregivers of children with CD.
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Article: Gastroenterology: Celiac Disease Source Type: research
The new Netflix documentary series profiles Dan Schneider, a small-town pharmacist who was one of the first people to identify and confront what we now know as America's opioid epidemic.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
This study examines the 12-month prevalence of mental disorders stratified by duration of sleep. Data were drawn from face-to-face interviews conducted in the National Epidemiologic Survey on Alcohol and Related Conditions III, a nationally representative survey of US adults (N = 36,309). There were 1893 (5.26%) participants who reported
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
ConclusionsFindings might have implications for targeting both psychological control and emotion regulation difficulties in personalized anxiety interventions during this high-risk developmental period.
Source: Journal of Behavior Therapy and Experimental Psychiatry - Category: Psychiatry Source Type: research
Every three minutes, a food allergy reaction sends someone to the emergency room in the US. Not only the number of people suffering from food allergies but also the complexity and severity of conditions are rising globally. Food scanners or portable devices could tell you the exact ingredients of the food on your plate; while apps and wearables help you deal with the effects of allergens. Here, I listed the best technologies combating food allergy! Food allergy on the rise Food allergy has been referred to as the second wave of the allergy epidemic, asthma being the first. Researchers estimate that up to 15 milli...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Food Portable Diagnostics applications apps digital digital health food allergy food scanner GC1 Personalized medicine technology wearables Source Type: blogs
More News: Allergy | Allergy & Immunology | Anxiety | Clinical Trials | Epidemics | Epidemiology | Food Allergy | Immunotherapy | Nutrition