How cells relieve DNA replication stress

(Institute for Basic Science) IBS scientists revealed that ATAD5 actively deals with replication stress, in addition to its known function to prevent such stressful situations. Though ATAD5 has been known as a tumor suppressor by maintaining genomic stability and suppressing tumorigenesis, it has been unclear whether the replication regulatory protein is also involved in the replication stress response. " We have identified the fundamental mechanism of replication stress control, which is a major cause of cancer. Hopefully our work will contribute to the development of cancer therapy, " explains director Myung.
Source: EurekAlert! - Biology - Category: Biology Source Type: news