Evaluation of the potential effect of dacomitinib, an EGFR tyrosine kinase inhibitor, on ECG parameters in patients with advanced non-small cell lung cancer

Conclusions There was a lack of a clinically relevant effect of dacomitinib on ECG parameters at dacomitinib concentrations comparable to those obtained at its highest therapeutic dosing regimen of 45  mg once daily. ClinicalTrials.gov identifier: NCT01858389.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research