The deleterious effects of smoking in bone mineralization and fibrillar matrix composition

ConclusionCigarette smoke exposure alters bone matrix composition and worsens bone mineralization, leading to bone fragility by increasing collagen V synthesis and deposition and impairing collagen I fibril forming and assembling. And these deleterious effects contributed to the worsening in fracture healing after tibia osteotomy.
Source: Life Sciences - Category: Biology Source Type: research