Chronic muscle stimulation improves muscle function and reverts the abnormal surface EMG pattern in Myotonic Dystrophy: a pilot study
Conclusions:
NMES determined a clear-cut improvement of both the muscular weakness and the sarcolemmal excitability alteration in our small group of DM1 patients. Therefore this rehabilitative approach, if confirmed by further extensive studies, could be considered early in the management of muscular impairment in these patients. An attractive hypothesis to explain our encouraging result could be represented by a functional inhibition of SK3 channels expressed in muscle of DM1 subjects.
Source: Journal of NeuroEngineering and Rehabilitation - Category: Rehabilitation Authors: Carmelo ChisariFederica BertolucciStefania DaliseBruno Rossi Source Type: research
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