IL-1 β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia

Neuroinflammation is thought to contribute to the pathogenesis of Alzheimer ’s disease (AD), yet numerous studies have demonstrated a beneficial role for neuroinflammation in amyloid plaque clearance. We have p...

Source: Journal of Neuroinflammation - December 10, 2019 Category: Neurology Authors: F átima Rivera-Escalera, Jonathan J. Pinney, Laura Owlett, Hoda Ahmed, Juilee Thakar, John A. Olschowka, Michael R. Elliott and M. Kerry O’Banion Tags: Research Source Type: research