Diabetic Peripheral Neuropathy Is Associated with Elevated Systolic Blood Pressure in non-hypertensive patients with type 2 diabetes and affect hypertensive management

Publication date: Available online 9 December 2019Source: Canadian Journal of DiabetesAuthor(s): Lingning Huang, Yongze Zhang, Yunmin Wang, Ximei Shen, Sunjie YanAbstractAimsInvestigate association between diabetic peripheral neuropathy (DPN)and above normal blood pressure in non-hypertensive patients with type 2 diabetes mellitus(T2DM). Compare the achievement of clinical target for DPN and non-DPN withT2DM .MethodsA retrospective survey was administered to 3810 patients with type 2 diabetes. Cases were grouped according to the Toronto Clinical Scoring System (TCSS): Non-DPN, Mild DPN, Moderate DPN and Severe DPN. 1835 patients (HT/non-HT = 1247/588) additionally received nerve conduction velocity test (NCV), after which a quadruple grouping of P ≤ 25% - P> 75% was calculated.ResultsIrrespective of hypertension, systolic blood pressure (SBP)and A1c levels in the DPN group were higher than non-DPN group levels (P
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research

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Conclusions/interpretationOur data show no association between Lp(a) plasma levels and theLPA SNPs with known effect on Lp(a) plasma levels with the development of microvascular complications in type 2 diabetes. This indicates that Lp(a) does not play a major role in the development of microvascular complications. However, larger studies are needed to exclude minimal effects of Lp(a) on the development of microvascular complications.
Source: Diabetologia - Category: Endocrinology Source Type: research
ConclusionsDiabetic nephropathy was common among Chinese patients with type 2 diabetes in primary care in Hong Kong. Early identification and control of the modifiable risk factors are of upmost importance in preventing the complication.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
AbstractAimsTo assess diabetes care delivery and prevention of short- and long-term diabetes-related complications in patients with type 2 diabetes mellitus (T2DM) in Vietnam.MethodsDiabCare Asia is an observational, non-interventional, cross-sectional study of hospital-based outpatient care for patients diagnosed with T2DM.ResultsA total of 1631 patients (mean age 62.7  years; 58.9% female) participated in the study. The percentage of patients with HbA1c
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research
Conclusion: More than half of the patients included in this study were found to have neuropathy, nearly half of whom presented with the severe form. The main risk factors were increasing age, increasing duration of diabetes, obesity, and hypertension. Diabetic peripheral neuropathy is underdiagnosed in northern Tanzania where screening for neuropathy is not routinely done. PMID: 31275374 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Conclusion: the subjects in the studied articles presented cardiovascular alterations, peripheral neuropathy, vestibular symptoms, difficulties in tasks/movements in challenging contexts, and falls.RESUMO Objetivo: verificar doen ças e sintomas associados às alterações do equilíbrio postural em indivíduos de meia-idade e idosos com Diabetes Mellitus tipo 2. Métodos: trata-se de uma revisão integrativa da literatura. A busca foi realizada a partir dos descritores: “ Dizziness ” , “ Vertigo ” , “ Vestibular Diseases ” , “ Labyri...
Source: Revista CEFAC - Category: Speech-Language Pathology Source Type: research
Conclusions: The study showed the severity of DPN was significantly associated with age, sex, duration of diabetes, HbA1c value, hypertension, and body mass index.
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research
This study aimed to compare the effect of high-intensity interval training (HIIT) with moderate-intensity continuous training (MCT) on endothelial function, oxidative stress and clinical fitness in patients with type 1 diabetes. Thirty-six type 1 diabetic patients (mean age 23.5 ± 6 years) were randomized into 3 groups: HIIT, MCT, and a non-exercising group (CON). Exercise was performed in a stationary cycle ergometers during 40 min, 3 times/week, for 8 weeks at 50–85% maximal heart rate (HRmax) in HIIT and 50% HRmax in MCT. Endothelial function was measured by flow-mediated dilation (FMD) [endothelium-depende...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
This article reviewed very recent papers (2016) discussing or bringing clinical evidences of the possible common pathways leading to diabetic foot syndrome (DFS) and increased mortality rates.Recent FindingsDiabetic patients with diabetic foot syndrome have a mortality rate greater than twofold when compared with non-ulcerated diabetics. In addition, the 5-year mortality rate following amputation is estimated at 39 –68%, a life expectancy comparable to aggressive types of cancer or advanced congestive heart failure. The majority of patients with diabetic foot ulcer also present insulin resistance, central obesity, dy...
Source: Current Atherosclerosis Reports - Category: Cardiology Source Type: research
Conclusion: Presence of orthostatic hypotension in diabetics is associated with higher prevalence of macrovascular and microvascular complications of diabetes mellitus and also with higher 10-year mortality.
Source: Hypertension - Category: Cardiology Authors: Tags: Poster Abstract Presentations Source Type: research
Conclusion High prevalence of complications of type 2 diabetes were observed especially in those with longer duration of diabetes and poor control.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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