Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study

Left atrial (LA) volumes are related to success of atrial fibrillation (AF) ablation, but the relation to other functional and structural parameters is less well understood. Our goal was to detect potential functional and structural predictors of arrhythmia recurrence after ablation using cardiac magnetic resonance imaging (CMRi) and to non-invasively assess the relation between LA functional and structural remodeling pre- and post-ablation.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research

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ConclusionBased on serial MRI, atrial ablation lesions are often fully mature before the typical 90 ‐day blanking period, which could support more timely clinical decision making for arrhythmia recurrence.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionsPulmonary vein isolation is the treatment of choice for symptomatic patients with paroxysmal and persistent drug-refractory AF. The reconnection of previously isolated pulmonary veins remains the major cause of AF recurrence. Novel ablation tools, such as balloon technologies or alternative energy sources, might help to overcome this limitation. Patients with non-paroxysmal AF and with AF recurrence might benefit from alternative ablation strategies. However, further studies are warranted to further improve our knowledge of the underlying mechanisms of AF and to obtain long-term clinical outcomes on new ablation techniques.
Source: Cardiology and Therapy - Category: Cardiology Source Type: research
Conclusion: NF formation post ‐ablation of AF is a novel marker of long‐term procedural outcome. Extensive NF is associated with significantly higher risk of atrial arrhythmia recurrence.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: ELECTROPHYSIOLOGY Source Type: research
Publication date: Available online 5 October 2019Source: Canadian Journal of CardiologyAuthor(s): Blandine Mondésert, Krishnakumar Nair, Christopher J. McLeod, Paul KhairyAbstractArrhythmias are a leading cause of morbidity in adults with congenital heart disease (CHD). Numerous challenges to managing arrhythmias include vascular access issues, intracardiac shunts, unconventional locations of the conduction system, and anatomical complexities. Technological advances are improving our ability to diagnose and treat arrhythmias. Implantable loop recorders and various technologies developed for consumers to record elect...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Background: Detection and treatment of atrial fibrillation (AF) is a major goal in preventing secondary stroke. Insertable cardiac monitors (ICMs) are available for diagnosis of arrhythmia monitoring in patients with cryptogenic stroke. Magnetic resonance imaging (MRI)-based diagnostic evaluation for acute ischemic stroke subtype classification is common in Japan and can be useful for specific diagnosis of cryptogenic stroke. Purpose: We aimed to investigate the detection rate of AF with an ICM in patients with cryptogenic stroke who were diagnosed by MRI.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
Abstract Atrial fibrillation (AF) is the most common arrhythmia associated with the risk of morbidity and mortality in clinical patients. AF is considered as an arrhythmia type that develops and progresses through close connection with cardiac structural arrhythmogenic substrates. Since the introduction of catheter ablation-mediated electrical isolation of arrhythmogenic substrates, cardiac imaging indicates improved treatment outcome and prognosis with appropriate candidate selection, ablation catheter guidance, and post-ablation follow-up. Currently, cardiac computed tomography (CCT) and cardiovascular magnetic ...
Source: Korean J Radiol - Category: Radiology Authors: Tags: Korean J Radiol Source Type: research
AbstractPurpose of ReviewAtrial fibrillation (AF) is the most frequent arrhythmia and also an important cause of morbidity, hospitalization, and mortality. Pulmonary vein isolation (PVI) is often the preferred therapy, but the incidence of recurrences is still significant. This review summarizes the contribution of atrial substrate identification using late gadolinium enhancement magnetic resonance imaging (LGE-MRI) to establish prognosis and to guide AF ablation.Recent FindingsLeft atrial (LA) fibrosis is thought to create the necessary substrate to sustain AF. The accuracy of LGE-MRI to identify areas of atrial fibrosis ...
Source: Current Cardiovascular Risk Reports - Category: Cardiology Source Type: research
Atrial fibrillation (AF) is the most prevalent form of cardiac arrhythmia. Current treatments for AF remain suboptimal due to a lack of understanding of the underlying atrial structures that directly sustain AF. Existing approaches for analyzing atrial structures in 3-D, especially from late gadolinium-enhanced (LGE) magnetic resonance imaging, rely heavily on manual segmentation methods that are extremely labor-intensive and prone to errors. As a result, a robust and automated method for analyzing atrial structures in 3-D is of high interest. We have, therefore, developed AtriaNet, a 16-layer convolutional neural network ...
Source: IEE Transactions on Medical Imaging - Category: Biomedical Engineering Source Type: research
, Anselme F Abstract BACKGROUND: Atrial fibrillation is the most common arrhythmia in adults. A relationship between epicardial adipose tissue and atrial fibrillation has recently been reported. AIM: To evaluate the impact of epicardial fat thickness on the outcome of patients who underwent a first pulmonary vein isolation procedure using a second-generation cryoballoon. METHODS: From February 2012 to February 2017, all patients who underwent a first pulmonary vein isolation procedure using a second-generation cryoballoon at Rouen University Hospital were included. Data were collected retrospectively. Ep...
Source: Archives of Cardiovascular Diseases - Category: Cardiology Authors: Tags: Arch Cardiovasc Dis Source Type: research
Conclusions: Six months of spaceflight may be sufficient to cause transient changes in left atrial structure and atrial electrophysiology that increase the risk of AF. However, there was no definite evidence of increased supraventricular arrhythmias and no identified episodes of AF.
Source: Circulation: Arrhythmia and Electrophysiology - Category: Cardiology Authors: Tags: Arrhythmias, Electrophysiology, Atrial Fibrillation, Magnetic Resonance Imaging (MRI) Original Articles Source Type: research
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