Pharmacological Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Alleviates Carbon Tetrachloride-Induced Liver Fibrosis in Mice.

CONCLUSIONS: The present findings suggest that activation of TRPV4 channels worsens liver fibrosis and that inhibition of TRPV4 channels may alleviate liver fibrosis in vivo. PMID: 31801932 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31801932?dopt=Abstract

Source: Journal of Nippon Medical School - December 7, 2019 Category: Universities & Medical Training Authors: Fu J, Du H, Zhang X, Xu X Tags: J Nippon Med Sch Source Type: research