Effect of Selenium Supplementation on Influenza Vaccination

Conditions:   Selenium Supplementation;   Influenza Vaccination Interventions:   Dietary Supplement: Selenium Supplementation;   Biological: Influenza vaccination Sponsors:   Huazhong University of Science and Technology;   The University of Queensland Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Publication date: Available online 17 January 2020Source: Microbes and InfectionAuthor(s): Kazuyuki Mimura, Soichiro Kimura, Chiaki Kajiwara, Sho Nakakubo, Matthew A. Schaller, Yoshikazu Ishii, Theodore J. Standiford, Steven L. Kunkel, Kazuhiro TatedaAbstractPneumococcal conjugate vaccination (PCV) may prevent influenza-related pneumonia, including Streptococcus pneumoniae pneumonia. To investigate PCV efficacy against secondary pneumococcal pneumonia following influenza, PCV was administered intramuscularly 2 and 5 weeks before S. pneumoniae serotype-3 colonization of murine nasopharynges followed by intranasal challenge ...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
Abstract Multiple genetically distinct influenza B/Victoria lineage viruses have cocirculated in the United States recently, circulating sporadically during the 2018-19 season and more frequently early during the 2019-20 season (1). The beginning of the 2019-20 influenza season in Louisiana was unusually early and intense, with infections primarily caused by influenza B/Victoria lineage viruses. One large pediatric health care facility in New Orleans (facility A) reported 1,268 laboratory-confirmed influenza B virus infections, including 23 hospitalizations from July 31 to November 21, 2019, a time when influenza ...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
chi Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs. It is necessary to understand the detailed and complex interactions between influenza virus and its host cells in order to identify successful strategies for therapeutic intervention. During viral entry, the cellular microenvironment presents invading pathogens with a series of obstacles that must be overcome to infect permissive cells. Influenza hijacks numerous host cell proteins and associated biological pathways during its journey into the cell, respon...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Flu season is always unpredictable. Different viral strains circulate each year, which makes forecasting the disease’s spread—and formulating the annual flu vaccine—an educated guessing game. Even so, the 2019-2020 flu season has been particularly unusual. Influenza B, the viral strain that usually circulates toward the end of flu season, instead emerged first this year, shifting usual transmission patterns. A vaccine mismatch and reduced immunity to influenza B may have contributed to the early and severe start of this flu season. What does that mean for the months ahead? TIME asked Lynnette Brammer, an ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease Source Type: news
Doubling the dose of influenza vaccine for pregnant women with HIV moderately improves immunogenicity compared to a single flu shot, but response remains well below that of pregnant women without HIV, a clinical trial shows.Reuters Health Information
Source: Medscape Pathology Headlines - Category: Pathology Tags: HIV/AIDS News Source Type: news
Four strains of the influenza virus have been identified through lab tests as circulating across the United States so far this flu season. This year's vaccine has two of them, but experts say vaccination still helps.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Influenza season is still in full swing and children are especially hard hit, in part as a result of a vaccine that is poorly matched to the currently predominant strain.Medscape Medical News
Source: Medscape Infectious Diseases Headlines - Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
AbstractPrevious studies of fetal death with maternal influenza have been inconsistent. We explored the effect of maternal influenza-like illness (ILI) in pregnancy on the risk of fetal death, distinguishing between diagnoses during regular influenza seasons and the 2009/2010 pandemic and between trimesters of ILI. We used birth records from the Medical Birth Registry of Norway to identify fetal deaths after the first trimester in singleton pregnancies (2006 –2013). The Norwegian Directorate of Health provided dates of clinical influenza diagnoses by primary-health-care providers, whereas dates of laboratory-confirme...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
Conditions:   Influenza Vaccine;   Behavioral Intervention;   Self-benefit;   Social-benefit Interventions:   Behavioral: Self-benefit message;   Behavioral: Other-benefit message Sponsors:   SB Istanbul Education and Research Hospital;   University of Nottingham Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsInfluenza A and B are often detected in children and adolescents with ILI episodes, with similar and mild presentation in outpatients. The mismatch between the circulating influenza viruses and the trivalent vaccine offered in Brazil may have contributed to the high frequency of influenza A and B in this population.
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
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