Baseline global longitudinal strain by computed tomography is associated with post transcatheter aortic valve replacement outcomes

Computed tomography angiography derived global longitudinal strain (CTA-GLS) has been shown to be feasible, however its prognostic value remains unclear in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). We evaluated the association of baseline CTA-GLS with outcomes including all-cause mortality and composite endpoint of death and heart failure hospitalization in 223 patients treated with TAVR. Patients with normal LVEF but reduced CTA-GLS had similar event rate to those with impaired LVEF, and higher than those with normal LVEF and preserved CTA-GLS. Baseline CTA-GLS assessment might be helpful in patients with difficult echocardiographic images undergoing TAVR evaluation.

Source: Journal of Cardiovascular Computed Tomography - December 4, 2019 Category: Radiology Authors: Miho Fukui, Jeffrey Xu, Floyd Thoma, Ibrahim Sultan, Suresh Mulukutla, Hesham Elzomor, Joon S. Lee, Thomas G. Gleason, Jo ão L. Cavalcante Source Type: research