Visible-light-induced intramolecular radical cascade of α-bromo-N-benzyl-alkylamides: a new strategy to synthesize tetracyclic N‑fused indolo[2,1-a]isoquinolin-6(5H)-ones

Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02294E, PaperXiaoshuang Gao, Chengyang Li, Yao Yuan, Xiaomin Xie, Zhaoguo Zhang Polycyclic indole scaffolds are ubiquitous in pharmaceuticals, natural products and materials science. Here in, we present a visible-light-initiated intramolecular aryl migration/desulfonylation/cyclization cascade reaction for the synthesis of tetracyclic indolo[2,1-a]isoquinolin-6(5H)-ones. This... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research