Whole blood levels of S1PR4 mRNA associated with cerebral vasospasm after aneurysmal subarachnoid hemorrhage.

CONCLUSIONS: The results, which are consistent with findings of previous experimental investigations conducted in animal models, support the role of S1PR4 and its ligand, sphingosine-1-phosphate (S1P), in arterial-associated vasoconstriction, which suggests that S1PR4 could be used as a biomarker for cerebral vasospasm in aSAH patients. PMID: 31783362 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31783362?dopt=Abstract

Source: Journal of Neurosurgery - November 28, 2019 Category: Neurosurgery Authors: Pulcrano-Nicolas AS, Jacquens A, Proust C, Clarençon F, Perret C, Shotar E, Puybasset L, Le Goff W, Degos V, Trégouët DA, Garnier S Tags: J Neurosurg Source Type: research