Upregulation of Glutamate-Aspartate Transporter by Glial Cell Line-Derived Neurotrophic Factor Ameliorates Cell Apoptosis in Neural Retina in Streptozotocin-Induced Diabetic Rats.
CONCLUSIONS: GDNF, administrated at the early stage of diabetes, could rescue retinal cells from neurodegeneration by upregulating the expression of GLAST.
PMID: 23870489 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Wang L, Deng QQ, Wu XH, Yu J, Yang XL, Zhong YM Tags: CNS Neurosci Ther Source Type: research