Adherence to COPD controller therapy: real life setting

Conclusion: We identified distinctive adherence trajectories as well as patient characteristics related to these trajectories.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Airway pharmacology and treatment Source Type: research

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Purpose of review Severe asthma is often associated with numerous comorbidities that complicate disease management and affect patient's outcomes. They contribute to poor disease control and mimic asthma symptoms. Although some comorbidities such as obstructive sleep apnea, bronchiectasis, and chronic obstructive pulmonary disease are generally well recognized, many other may remain undiagnosed but may be detected in an expert specialist setting. The management of comorbidities seems to improve asthma outcomes, and optimizes therapy by avoiding overtreatment. The present review provides recent knowledge regarding the most...
Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: ASTHMA: Edited by Nicola A. Hanania, Zuzana Diamant, and Maarten van den Berge Source Type: research
Introduction: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary (COPD), are usually accompanied by several comorbidities. Aim of the study was to assess the prevalence of comorbidities in OSA and COPD-OSA overlap syndrome (OS) patients and to explore differences between these two groups.Methods: Included were consecutive OS (n=163, 138 males, AHI>5/h and FEV1/FVC5/h and FEV1/FVC>0.7), matched in terms of gender, age, BMI, and smoking history, diagnosed with polysomnography and pulmonary function testing.Results: As mentioned, the two groups were matched in age (p=0.221), BMI (p=0.496) and neck circumfer...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research
Introduction: Many individuals with chronic obstructive pulmonary disease (COPD) report suffering from chronic pain, which is often underestimated by physicians. It could affect the patient’s quality of life.Aims and objectives: To determine common origins of chronic pain in individuals with COPD, its impact on their quality of life and its contribution to the emergence of anxiety and depression symptoms.Methods: A cross-sectional study of male individuals with COPD was conducted at the Pneumology Department of Hedi Chaker Hospital in Sfax (Tunisia) between January 10 and February 10 2018. Dyspnea severity was strati...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Source Type: research
Background: Phenotypic differences between early-onset (EODA) and adult-onset (AODA) difficult asthma in adulthood are not well described.Aim: To characterise EODA and AODA in difficult asthma.Methods: The Wessex AsThma CoHort of difficult asthma (WATCH) is a longitudinal study at University Hospital Southampton (UHS) UK set up in 2015. To date, 380 patients are enrolled from the UHS tertiary difficult asthma clinic. Clinical features of EODA (age ≤18 yrs) and AODA (age>18 yrs) are presented here.Results: Of 368 patients with available data, 51.6% had EODA and 48.4% AODA (median age of onset 4.0 yrs v 40.5 yrs respectively (p
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring Airway Disease Source Type: research
Background: Multiple co-morbidities are associated with disease control, healthcare utilization and quality of life in difficult asthma.Aim: To evaluate the prevalence of comorbidities in patients with difficult asthma in the Wessex AsThma CoHort of difficult asthma (WATCH).Methods: Our prospective observation cohort study has enrolled 380 patients with severe asthma. History of co-morbidities is collected at enrolment. Data is presented as percentages and chi squared tests were used to calculate differences between groups.Results: Comorbidity(n)Prevalence (%)Gender Difference(male % vs female %)Age of Onset Difference (ea...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring Airway Disease Source Type: research
Conclusions: COPD women, as compared with men, had similar distribution of disease severity and more exacerbations, despite milder smoking history. Women had higher prevalence of anxiety, valvular disease, thyroid disease, but lower prevalence of ischemic heart and cerebral disease and neoplastic disease.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical Problems Source Type: research
Background: Personalised therapy for COPD patients is debated. We investigated whether the rate of FEV1 decline differs between patients with and without ICS-containing medications, stratified by blood EOS level.Methods: The UK Clinical Practice Research Datalink (primary care records) and Hospital Episode Statistics (hospital records) were used to identify COPD patients with ≥2 FEV1 measurements ≥6 months apart. Follow-up started from first FEV1 until censoring at death, leaving database or first ICS-containing prescription (if not baseline ICS-containing user). The nearest blood EOS 2 years prior to the start of fo...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
The objective of this review is to describe current knowledge and clinical implications of the overlapping features of asthma and COPD, and discuss the prevalence and impact of comorbidities, such as osteoporosis, cardiovascular disease, gastroesophageal reflux disease, and depression, in this subgroup of patients.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
Conclusion: In a clinical practice setting, the majority of patients with moderate airflow limitation had significant comorbidities that were more common in more symptomatic ones. Since comorbidities have impact on patient outcomes, there is a need for careful identification and management of these, especially in the more symptomatic COPD patients.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 1.12 Clinical Problems - COPD Source Type: research
There are several days and the month itself dedicated to raising awareness about various health topics in November. From the National Health Observances put together by the National Health Information Center, we have American Diabetes Month, Bladder Health Month, COPD Awareness Month, Diabetic Eye Disease Month, Lung Cancer Awareness Month, Lung Cancer Awareness Month, National Alzheimer’s Disease Awareness Month, National Family Caregivers Month, National Healthy Skin Month, National Hospice Palliative Care Month, and National Stomach Cancer Awareness Month. In addition these are special days and weeks in November, ...
Source: BHIC - Category: Databases & Libraries Authors: Tags: General Public Health Source Type: blogs
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