Aspirated bile acids affect lung immunity and function

Conclusion: BAs strongly associate to bacterial infections confirming their involvement in allograft dysfunction. Reduced bronchial reactivity suggests that BAs may affect both lung innate defense and function. The effect of BAs on airway reactivity may impair airway clearance and in turn promote infections.

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Urso, A., Perez-Zoghbi, J., Nandakumar, R., Cremers, S., Bunnett, N., Emala, C., DOvidio, F. Tags: Transplantation Source Type: research