Discriminative analysis of early-stage Alzheimer's disease and normal aging with automatic segmentation technique in subcortical gray matter structures: a multicenter in vivo MRI volumetric and DTI study.

CONCLUSION: Pathological changes takes place in the hippocampus and other subcortical gray matter structures in early-stage AD. Diffusive imaging has great diagnostic significance in early-stage AD. The combination of both imaging modalities can lead to better discrimination between early-stage AD and normal aging. PMID: 23878359 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23878359?dopt=Abstract

Source: Acta Radiologica - July 22, 2013 Category: Radiology Authors: Li YD, He HJ, Dong HB, Feng XY, Xie GM, Zhang LJ Tags: Acta Radiol Source Type: research