Cancer warning: Radiation from CT scans linked to increased risk of thyroid cancer

CANCER currently has no cure, but research is looking into what can increase the risk of it developing and how to prevent it. A new study has found exposure to radiation from CT scans is associated with higher risks of developing thyroid cancer and leukaemia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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ConclusionsWe interpreted the incidence statistics of cancer for Fukushima residents between 2008 and 2015. Our results will provide fundamental statistics for subsequent researchers to assess the relationship between the disaster and cancer incidence among Fukushima residents in the long term. PMID: 32963211 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
Abstract BACKGROUND: Proportionate female representation in health research is necessary for scientific rigour and health equity. We aimed to assess the representation of females in clinical trials leading to US Food and Drug Administration (FDA) cancer drug approvals. METHODS: Trials supporting US FDA cancer drug approvals between July 2008 - June 2018 were sourced from PubMed and ClinicalTrials.gov. The ratio of female to male trial enrollment was compared with cancer incidence and mortality in the US using International Agency for Research on Cancer (IARC) data. Reproductive tract and breast cancers were e...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
The Trinity nuclear test, conducted in 1945, exposed residents of New Mexico to varying degrees of radioactive fallout. Companion papers in this issue have detailed the results of a dose reconstruction that has estimated tissue-specific radiation absorbed doses to residents of New Mexico from internal and external exposure to radioactive fallout in the first year following the Trinity test when more than 90% of the lifetime dose was received. Estimated radiation doses depended on geographic location, race/ethnicity, and age at the time of the test. Here, these doses were applied to sex- and organ-specific risk coefficients...
Source: Health Physics - Category: Radiology Tags: PAPERS Source Type: research
esco Albano Immunomodulatory drugs (IMiDs) are analogs of thalidomide. They have immunomodulatory, antiangiogenic and proapoptotic properties and exert a role in regulating the tumor microenvironment. Recently IMiDs have been investigated for their pleiotropic properties and their therapeutic applications in both solid tumors (melanoma, prostate carcinoma and differentiated thyroid cancer) and hematological malignancies. Nowadays, they are applied in de novo and relapsed/refractory multiple myeloma, in myelodysplastic syndrome, in del5q syndrome with specific use of lenalidomide and B-cell lymphoma. Several studies hav...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
About one-third of physicians have ordered thyroid ultrasound scans for patients...Read more on AuntMinnie.comRelated Reading: Is thyroid cancer overdiagnosed for 9/11 first responders? Does thyroid cancer screening lead to overdiagnosis? CT radiation increases risk of thyroid cancer, leukemia AI boosts ultrasound for thyroid cancer screening New thyroid test could help patients avoid surgery
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Abstract In various cancers, high-grade tumor and poor survival rate in patients with upregulated lncRNAs UCA1 have been confirmed. Urothelial carcinoma associated 1 (UCA1) is an oncogenic non-coding RNA with a length of more than 200 nucleotides. The UCA1 regulate critical biological processes that are involved in cancer progression, including cancer cell growth, invasion, migration, metastasis, and angiogenesis. So It should not surprise that UCA1 overexpresses in variety of cancers type, including pancreatic cancer, ovarian cancer, gastric cancer, colorectal cancer, breast cancer, prostate cancer, endometrial c...
Source: Current Molecular Medicine - Category: Molecular Biology Authors: Tags: Curr Mol Med Source Type: research
Contributors : Anuhar Chaturvedi ; Razif Gabdoulline ; Michael HeuserSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMutations in the enzymes IDH1 and IDH2 have been identified in a wide variety of tumors like glioma, chondrosarcoma, thyroid cancer, lymphoma, melanoma, and in acute myeloid leukemia. Mutated IDH1/2 produces the metabolite 2-hydroxyglutarate (2HG), which interferes with epigenetic regulation of gene expression, and thus may promote tumorigenesis. Data for IDH1 inhibitors show that 30-40% of AML patients respond to monotherapy with a median duration of response of 8 mont...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Anuhar Chaturvedi ; Razif Gabdoulline ; Michael HeuserSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensMutations in the enzymes IDH1 and IDH2 have been identified in a wide variety of tumors like glioma, chondrosarcoma, thyroid cancer, lymphoma, melanoma, and in acute myeloid leukemia. Mutated IDH1/2 produces the metabolite 2-hydroxyglutarate (2HG), which interferes with epigenetic regulation of gene expression, and thus may promote tumorigenesis. Data for IDH1 inhibitors show that 30-40% of AML patients respond to monotherapy with a median duration of response of 8 months, su...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by genome tiling array Homo sapiens Source Type: research
Conclusions: Stem cells-targeted α-particle therapy with 211At-CXCR4 mAb is promising for AML , because absorbed dose delivered to target cells to normal organs would be high enough based on the dosimetry evaluation using tumor xenograft and sphere model. Acknowledgements: This study was financially supported by JSPS KAKENHI Grant Number JP16H05393.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Basic Oncology & amp; Translational (Poster Session) Source Type: research
Thyroid cancer diagnoses are up to three times more common in 9/11 first responders...Read more on AuntMinnie.comRelated Reading: Does thyroid cancer screening lead to overdiagnosis? CT radiation increases risk of thyroid cancer, leukemia AI boosts ultrasound for thyroid cancer screening New thyroid test could help patients avoid surgery US screening data from Fukushima shed light on thyroid cancer in kids
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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