Changes of plasma fibroblast growth factor-21 (FGF-21) in oral glucose tolerance test and effects of metformin on FGF-21 levels in type 2 diabetes mellitus.

Conclusion: FGF-21 does not seem to be involved in short-term regulation of glycaemia in human subjects, and the change in OGTT delayed in T2DM. FGF-21 may participate in the processing of metformin, improving glucose and insulin sensitivity. (Pol J Endocrinol 2013; 64 (3): 220-224). PMID: 23873427 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/23873427?dopt=Abstract

Source: Endokrynologia Polska - July 24, 2013 Category: Endocrinology Authors: Zhang M, Liu Y, Xiong ZY, Deng ZY, Song HL, An ZM Tags: Endokrynol Pol Source Type: research