Antibiotic Therapy In Respiratory Tract Infections

Condition:   Community-Acquired Pneumonia Interventions:   Drug: Predetermined treatment duration;   Drug: Variable treatment duration Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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In conclusion, antibiotic therapy was often incomplete, was generally guideline discordant, exhibited limited diversity of selection, and frequently lacked diagnostic confirmation. These data, combined with local susceptibility patterns, may be used to foster AMS efforts for improved compliance with guidelines at MZRH in the future. PMID: 31802729 [PubMed - as supplied by publisher]
Source: Am J Trop Med Hyg - Category: Infectious Diseases Authors: Tags: Am J Trop Med Hyg Source Type: research
We hereby report a case of subclinical community ‐acquiredAcinetobacter pneumonia in association with a mature cystic teratoma masquerading as a lung abscess. A 22 ‐year‐old lady presented with fever and right pleuritic chest pain with chest X‐ray showing a right suprahilar shadow. Her symptoms largely subsided with antibiotic therapy but the shadow remained unresolved. Computerized tomography (CT) scan of thorax showed consolidation over the anterior se gment of the right upper lobe with a hypodense area suspicious of a lung abscess. Fine needle aspirates of the lesion grewAcinetobacter baumannii twice but the sha...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
AbstractPrevalence and clinical impact of viral respiratory tract infections (VRTIs) on community-acquired pneumonia (CAP) has not been well defined so far. The aims of this study were to investigate the prevalence and the clinical impact of VRTIs in patients with CAP. Prospective study involving adult patients consecutively admitted at medical wards for CAP and tested for VRTIs by real-time PCR on pharyngeal swab. Patients ’ features were evaluated with regard to the presence of VRTI and aetiology of CAP. Clinical failure was a composite endpoint defined by worsening of signs and symptoms requiring escalation of ant...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
BACKGROUND: The clinical utility of procalcitonin in the diagnosis and management of pneumonia remains controversial. METHODS: We assessed the clinical utility of procalcitonin in 2 prospective studies: first, a multicenter diagnostic study in patients presenting to the emergency department with acute dyspnea to directly compare the diagnostic accuracy of procalcitonin with that of interleukin 6 and C-reactive protein (CRP) in the diagnosis of pneumonia; second, a randomized management study of procalcitonin guidance in patients with acute heart failure and suspected pneumonia. Diagnostic accuracy for pneumonia as central...
Source: Clinical Chemistry - Category: Chemistry Authors: Tags: Infectious Disease Source Type: research
ConclusionPediatricians should consider the diagnosis of Kawasaki disease in the presence of pneumonia and pleural effusion that is nonresponsive to antibiotic therapy. This will prevent delay in diagnosis and the adverse consequences of the disease.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
ConclusionsFilmArray PP offers a rapid and sensitive diagnostic method for lower respiratory tract infections. However, clinical correlation is advised to determine its significance in interpreting multiple pathogens and detection of genes involved in antimicrobial resistance.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
CONCLUSIONS: FilmArray PP offers a rapid and sensitive diagnostic method for lower respiratory tract infections. However, clinical correlation is advised to determine its significance in interpreting multiple pathogens and detection of genes involved in antimicrobial resistance. PMID: 31806539 [PubMed - as supplied by publisher]
Source: Journal of Microbiology, Immunology, and Infection - Category: Microbiology Authors: Tags: J Microbiol Immunol Infect Source Type: research
There is little descriptive data on Stenotrophomonas maltophilia hospital-acquired pneumonia (HAP) in critically ill patients. The optimal modalities of antimicrobial therapy remain to be determined. Our objectiv...
Source: Critical Care - Category: Intensive Care Authors: Tags: Research Source Type: research
CONCLUSIONS: Chorioamnionitis and endometritis were the most common causes of sepsis, together accounting for about half of cases. Notable differences were observed in the sensitivity and specificity of sepsis screening tools with the highest to lowest sensitivity being SIRS, MEW, and qSOFA criteria, and the highest to lowest specificity being qSOFA, MEW, and SIRS. Mortality was doubled in the cohort of patients who received antibiotics after>1 hour. Clinicians need to be vigilant to identify cases of peripartum sepsis early in its course and prioritize timely antibiotic therapy. PMID: 31743182 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
Treatment of CAP at the patient with cardiovascular diseases is difficult task because except effectiveness of antibiotics risk of adverse events and drug interaction between basic cardiovascular medicines and antibiotics should be taken into account. We have created SS. Using it doctor enters complete clinical diagnosis of patient and receives recommended by guidelines list of medications for therapy with consideration of their benefit and dangerous interactions. We compared efficacy and safety of ordinarily prescribed treatment of 157 CAP patients with cardiovascular diseases (control group - CG) and using SS prescribed ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: M-health/e-health Source Type: research
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