Haploidentical Bone Marrow Transplant With or Without NK Cell Infusion in AML and MDS

Conditions:   Acute Myeloid Leukemia;   Myelodysplasia Intervention:   Biological: NK cells Sponsors:   Fondazione Policlinico Universitario Agostino Gemelli IRCCS;   Ministry of Health, Italy Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

Related Links:

After a bone marrow transplant, a man with leukemia found that his donor ’s DNA traveled to unexpected parts of his body. A crime lab is now studying the case.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Forensic Science Genetics and Heredity Bone Marrow DNA (Deoxyribonucleic Acid) Transplants Crime and Criminals Source Type: news
Conditions:   Leukemia;   Lymphoma;   Blood Cancer;   Myelodysplastic Syndrome;   Acute Myelogenous Leukemia;   Non-Hodgkins Lymphoma Intervention:   Other: Bone Marrow Transplant (BMT) Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Institutes of Health (NIH);   National Institute on Aging (NIA) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Bone Marrow Transplantation, Published online: 03 December 2019; doi:10.1038/s41409-019-0762-3Excellent outcome after consolidation with autologous transplantation in patients with core binding factor acute myeloid leukemia
Source: Bone Marrow Transplantation - Category: Hematology Authors: Source Type: research
Bone Marrow Transplantation, Published online: 29 November 2019; doi:10.1038/s41409-019-0761-4HLA-mismatched microtransplantation for relapsed or refractory acute myeloid leukemia as a bridge to allogeneic hematopoietic stem cell transplantation
Source: Bone Marrow Transplantation - Category: Hematology Authors: Source Type: research
UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In astudy published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions.Multiplying blood stem cells in conditions outside the human body could greatly improve treatment options for blood cancers like leukemia and for many inherited blood diseases.Dr. Hanna Mikkola, a member of the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and senior author of the study, h...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Work on bone marrow transplantation from haploidentical donor has been proceeding for over 20 years all over the world and new transplant procedures have been developed. To control both graft rejection and graft vs. host disease, some centers have preferred to enhance the intensity of the conditioning regimens and the post-transplant immune suppression in the absence of graft manipulation; others have concentrated on manipulating the graft in the absence of any additional post-transplant immune suppressive agent. Due to the current high engraftment rates, the low incidence of graft-vs.-host disease and regimen related mort...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conditions:   Acute Myeloid Leukemia;   Myelodysplasia Intervention:   Biological: NK cells Sponsors:   Fondazione Policlinico Universitario Agostino Gemelli IRCCS;   Ministry of Health, Italy Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Bone Marrow Transplant | Italy Health | Leukemia | Research | Transplants