Microstructural tissue damage in normal appearing brain tissue accumulates with Framingham Stroke Risk Profile Score: Magnetization transfer imaging results of the Austrian Stroke Prevention Study

Conclusion: Increasing risk for stroke leads to microstructural brain changes invisible by standard MRI. The validity, the underlying pathogenic mechanisms and the clinical importance of these abnormalities needs to be further determined.

Source: Clinical Neurology and Neurosurgery - January 8, 2013 Category: Neurosurgery Authors: Nina Homayoon, Stefan Ropele, Edith Hofer, Petra Schwingenschuh, Stephan Seiler, Reinhold Schmidt Tags: Original articles Source Type: research