The association of AGO1 (rs595961G> A, rs636832A> G) and AGO2 (rs11996715C> A, rs2292779C> , rs4961280C> A) polymorphisms and risk of recurrent implantation failure.

The association of AGO1 (rs595961G>A, rs636832A>G) and AGO2 (rs11996715C>A, rs2292779C>, rs4961280C>A) polymorphisms and risk of recurrent implantation failure. Biosci Rep. 2019 Nov 14;: Authors: Ryu CS, Kim YR, Kim JO, An HJ, Cho SH, Ahn EH, Kim JH, Lee WS, Kim NK Abstract Recurrent implantation failure (RIF) is a common reproductive clinical condition treated by fertility specialists at in vitro fertilization (IVF) clinics. Several factors affect embryo implantation including the age of the female, the quality of embryos and the sperm, genetics, immunologic factors. Here, we investigated the association of Argonaute 1 (AGO1) and Argonaute 2 (AGO2) polymorphisms and RIF. We collected blood samples from 119 patients with RIF and 235 controls. Genetic polymorphisms were detected by polymerase chain reaction (PCR) - restriction fragment length polymorphism analysis and real-time PCR. We found that the AGO2 rs4961280C>A polymorphism (adjusted odds ratio [AOR] = 1.853; P=0.036) was significantly associated with RIF. Furthermore, in RIF patients with three or more consecutive implantation failure, the AGO2 rs4961280C>A CA genotype (AOR=1.956; P=0.027) and dominant model (AOR=2.034; P=0.018) were both significantly associated with prevalence of RIF. An analysis of variance revealed that patients with the AGO2 rs2292779C>G genotypes (CC: 6.52±2.55; CG: 7.46±3.02; GG: 8.42±2.74; P=0.044) and the dominant model (CC: 6....
Source: Bioscience Reports - Category: Biomedical Science Authors: Tags: Biosci Rep Source Type: research

Related Links:

Publication date: Available online 13 July 2020Source: Journal of Sound and VibrationAuthor(s): Paruchuri Chaitanya, Phillip Joseph, Tze Pei Chong, Matthew Priddin, Lorna Ayton
Source: Journal of Sound and Vibration - Category: Physics Source Type: research
Publication date: Available online 12 July 2020Source: Journal of Sound and VibrationAuthor(s): Mehdi Bohlooly, Mohammad Ali Kouchakzadeh, Babak Mirzavand, Mohammad Noghabi
Source: Journal of Sound and Vibration - Category: Physics Source Type: research
Publication date: Available online 13 July 2020Source: Journal of Physics and Chemistry of SolidsAuthor(s): Lanli Chen, Liyang Zhang, Zhihua Xiong, Yuanyuan Cui, Hongjie Luo, Yanfeng Gao
Source: Journal of Physics and Chemistry of Solids - Category: Physics Source Type: research
Surface channel waveguides (WGs) based on a half-ring (40 – 60- µ m-diameter) depressed-index cladding (type III) geometry are ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
By considering parity-defined Laguerre – Gaussian (LG) and Hermite – Gaussian (HG) beams as input modes, we present arguments ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
Polarization-multiplexed dual-comb fiber lasers enable significant applications in dual-comb spectroscopy and optical sensing. However, the ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
Gas-filled hollow-core photonic crystal fiber (PCF) is used for efficient nonlinear temporal compression of femtosecond laser pulses, two ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
Single-photons with high spectro-temporal purity are an essential resource for quantum photonic technologies. The highest reported purity ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
We present a compact scheme for the generation of high-dimensional states of light encoded in the transverse linear momentum of photons ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
A potential control over the position of maxima of scattering and absorption cross sections can be exploited to better tailor nanoparticles ...
Source: Optics Letters - Category: Physics Authors: Source Type: research
More News: Allergy & Immunology | Biomedical Science | Genetics | Reproduction Medicine | Study